- This episode is Grapefruit and Grandpa Lemon's sixth appearance each.
- This is the first and only time Orange got hurt due to Marshmallow's anger.
- This is the second time that Celery appeared, the first is Excess Cabbage.
- There is a hidden message in the title card: If you saw this, type APEFRUIT! in the comments!
- Midget Apple was shown being able to move (hopping on Grandpa Lemon's Motorcycle), making him the sixth character to do so.
- This is the second time Grandpa Lemon was on his motorcycle, the first being Rap-berry.
- This is the first time someone shouted "Knife", but Knife didn't appear.
- This is the second time someone other than Orange shouted "Knife!", first being Jalapeño.
- This is the first time the kitchen got caught on fire.
- Usually cheerful and giggling, this is the first time Marshmallow shows a negative emotion.
- At 1:44 and 3:54, mustachios can be seen. (The 3:54 one is hard to find; he is in the bottom left corner, but can easily be seen in full screen mode.)
- This is the first episode where Marshmallow demonstrates his ability to explode when he gets furious enough, and also, this reveals that his long temper isn't infinite.
- It is unknown what happened to Celery when Marshmallow blew up. It's possible that either he died in the explosion, or he pulled a "Oh, that's it. I'm outta here." like Midget Apple did, albeit offscreen.
- There is actually a game called Best Fiends Forever by Seriously Digital Entertainment.
- When Marshmallow says "You've got mail" it is similar to the AOL Instant Messenger sound clip, You've got mail.
- Before and During the Explosion, you can see that there is a claw-digger and dirt in a construction pit in the back of the house.
- Marshmallow shows his anger-exploding issue again in Annoying Orange vs. Angry Birds.
- Orange and Pear's faces from the Annoying Pear thumbnail appears on the video's thumbnail.