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Charlie the Guinea Pig (also known as Charlie the "Drunk" Guinea Pig) is a minor character who only appeared in the Annoying Orange episode "Annoying Saw 2: The Annoying Death Trap".

He is played by Ian Hecox of Smosh. A running gag is that he is morbidly inebriated and drunk, which makes him act obstreperous, uncomplimentary, unreasonable, obnoxious, bitter, rude, insulting, argumentative, and opprobrious.

The theme song in the original episodes explains that Charlie was adopted by Ian and Anthony (from Smosh), when the two found Charlie in a trash can. Charlie has a slurred English accent, and is constantly drinking booze (although he has never actually been shown drinking it). Because of his drinking problem, Charlie is idiotic, cranky, and rude.

However, if he sobers up for more than a few days, he will begin to shoot lasers from his eye uncontrollably. Although he died from prostate cancer in the final episode of his channel, Ask Charlie, he was still alive in real life until his death in 2015.

He currently appears in Smosh as a ghost.

Main Characters Recurring Characters TV Exclusive Characters
Orange Apple Nerville
Pear Squash Apple
Midget Apple Knife Coconut
Marshmallow Liam the Leprechaun Peach
Passion Fruit Captain Obvious Tomato
Grapefruit Nude Dude Banana
Grandpa Lemon Dr. Bananas Pineapple
Orange's Sister Zoom Ginger
Corey Gaming Grape Broccoli Overlord